American researchers have pinpointed higher blood-sugar levels play significant role in increasing the risk of developing Alzheimer’s disease.
While the disease is seen more in diabetes, the new study tried to explore how blood sugar was associated with the mind-robbing disease.
The study researchers examined blood sugar in all sorts of people, with and without diabetes, to find the link, according to the paper published in The New England Journal of Medicine.
From among 2067 members, some patients had Type 2 diabetes when the study began, but most did not have the disease. None had dementia.
Over the course of the study (nearly seven years), the results unraveled that about a quarter of participants developed dementia of some kind, primarily Alzheimer’s disease or vascular dementia.
“We found a steadily increasing risk associated with ever-higher blood glucose levels, even in people who did not have diabetes,” explained the lead author Dr. Paul Crane, the associate professor of medicine at the University of Washington.
“The association with dementia kept climbing with higher blood sugar levels and, at the other end of the spectrum, continued to decrease with lower levels,” researchers say.
The recent study proves that the brain is a target organ for damage by high blood sugar, experts say.
Meanwhile, a previous study found that some medicines prescribed in patients suffering from type-2 diabetes such as Metformin were effective in treating Alzheimer’s disease.
Researchers suggest that keeping glucose at a healthy level by recommended practices can avert risk of developing the disease.
Alzheimer’s disease is the most common form of dementia that cannot be cured.
The cause for most Alzheimer’s cases is still unknown, except for 1% to 5% of cases where genetic differences have been identified.
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